The crystal structure of GNMT complexed with 5-CH(3)-THF revealed that there are two folate molecules bound to one tetrameric form of GNMT, which is a basis for ...

1.20) is a major protein in rat liver that binds 5-methyltetrahydrofolate polyglutamate in vivo. This enzyme is believed to function in the regulation of the ...

Purification of glycine N-methyltransferase resulted in the separation of two enzyme species, one that contained bound folate and one that did not. Each species ...

Glycine N-methyltransferase, an enzyme that uses S-adenosylmethionine to methylate glycine ... folate binding protein of rat liver (Cook, R.J. and Wagner, C.

1.20) is a major protein in rat liver that binds 5-methyltetrahydrofolate polyglutamate in vivo. This enzyme is believed to function in the regulation of the ...

GNMT activity is inhibited by allosteric binding of 5-methyl THF, the synthesis of which is inhibited by SAM [8]. The activity of GNMT can therefore be ...

Three human cases having mutations in the glycine N-methyltransferase (GNMT) gene have been reported. This enzyme transfers a methyl group from S-adenosylm.

Features ; Binding site, 4, (6S)-5-methyl-5,6,7,8-tetrahydrofolate 1 (UniProtKB | ChEBI ); ligand shared between tetrameric partners 1 publication. Imported.

Dec 9, 2016 · Consistent with this interpretation, the bound SAH can be replaced by the methyl donor S-adenosyl-L-methionine without triggering the ...

May 25, 2022 · Catalyzes the methylation of glycine by using S-adenosylmethionine (AdoMet) to form N-methylglycine (sarcosine) with the concomitant ...